Tiger cubs go missing, and Rosie Trevanion gets engaged. Sarah returns briefly to supply teaching at the local school. However, his cooperation turns to hostility when he thinks he's been betrayed. Series 3 (2008): The Trevanions attempt to build an animal hospital at Leopards Den initially a friendly collaboration with Elliot Kriel, the new American owner of Mara.

When Dup is nearly killed and Danny seriously injured in a lion attack, Danny's confidence is shattered, and Fatani takes advantage by trying to buy them out in a moment of weakness. A bitter inspector refuses to renew their permit to house wild animals Sarah's difficult mother Caroline arrives and a plane crashes nearby, exposing the family to the threat of deadly disease from a contraband chimpanzee. Mara's owner is killed while illegally hunting a rhino, and the new manager Cedric Fatani seems even more intent on causing mayhem, as he diverts water from the shared spring, causing the death of many Leopards Den animals. Series 2 (2007): The Trevanions struggle financially and attempt to satisfy their first guests' desire for acceptable accommodations and game drives. They face many challenges, including a deadly snakebite, an anthrax outbreak that threatens the reserve's stock starving lions runaway children uninvited guests and competition from Mara, the larger game park next door whose owner, Alex Tate, doesn't share Danny's values and tries to make a move on Sarah. The Trevanions begin settling into life in the African bush, and Danny grows into his role as a gifted vet treating stray cheetahs, elephants, etc. He persuades them to stay and enter into a business partnership to restore the property as a game reserve for wild animals.

Arriving at Leopards Den, they meet Anders Du Plessis ('Dup') whose family has owned the property for over 100 years. His wife Sarah suggests a family vacation to Africa to rehabilitate it. Series 1 (2006): The Trevanion family is introduced at home in Bristol, England, where an abandoned vervet monkey is brought into Danny's veterinary surgery.

Tv show wild at heart